Investigating the effect of polarity of stationary and mobile phases on retention of cannabinoids in normal phase liquid chromatography
| Autor: | Chiara De Luca, Alessandro Buratti, Yannick Krauke, Svea Stephan, Kate Monks, Virginia Brighenti, Federica Pellati, Alberto Cavazzini, Martina Catani, Simona Felletti |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Chromatography
Liquid Cannabinoids Cannabis sativa L Hemp HPLC Normal phase Polar-bonded phases Alcohols Chromatography High Pressure Liquid Chromatography Liquid Solvents Cannabis Biochemistry Analytical Chemistry NO High Pressure Liquid Cannabinoids Cannabis sativa L Hemp HPLC Normal phase Polar-bonded phases |
| Popis: | This work reports about a screening of four adsorbents with different polarity employed for the separation of the main phytocannabinoids contained in Cannabis sativa L., under normal phase liquid chromatography (NPLC). The effect of polarity and type of interaction mechanisms of the adsorbents (namely Si-, CN-, Diol-, and NH2-based SPs) on retention has been investigated under a variety of conditions either by using different combinations of apolar solvents (heptane or hexane) and alcohols (ethanol or isopropanol). The columns have also been employed for the separation of a real cannabis sample. |
| Databáze: | OpenAIRE |
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