Thymosin beta 4: a ubiquitous peptide in rat and mouse tissues
| Autor: | Ewald Hannappel, J Morgan, G J Xu, B L Horecker, J Hempstead |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
medicine.medical_specialty
Mice Nude Peptide Spleen Thymus Gland Biology Mice Species Specificity Internal medicine medicine Animals Ascitic Fluid Tissue Distribution Beta (finance) Chromatography High Pressure Liquid chemistry.chemical_classification Ascitic fluid Thymus Hormones Multidisciplinary Lung Macrophages Thymosin Brain Rats Thymosin beta-4 medicine.anatomical_structure Endocrinology chemistry Research Article |
| Zdroj: | Proceedings of the National Academy of Sciences. 79:2172-2175 |
| ISSN: | 1091-6490 0027-8424 |
| DOI: | 10.1073/pnas.79.7.2172 |
| Popis: | Thymosin beta 4, recently isolated from calf thymus, is present in a number of rat and mouse tissues, including spleen, thymus, brain, lung, liver, and heart muscle. High concentrations are found in peritoneal macrophages, suggesting that its occurrence in other tissues may be related to the presence of macrophages or macrophage-like cells in these tissues. The conclusion that "thymosin" beta 4 does not originate solely in the thymus gland is supported by the high concentrations found in tissues of athymic (nu/nu) mice. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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