Cellular expression and genetic control of ABH antigens in primary sensory neurons of marmoset, baboon and man
| Autor: | David R. Davies, A. M. Dalix, Rafael Oriol, Rosella Mollicone, Beryl Evans |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
Immunology
Fluorescent Antibody Technique Antibodies ABO Blood-Group System Antigen Ganglia Spinal biology.animal ABO blood group system medicine Animals Humans Immunology and Allergy Neurons Afferent Trigeminal nerve biology Marmoset Molecular biology Rats Ganglion medicine.anatomical_structure Neurology Callitrichinae Neurology (clinical) Nucleus Unipolar neuron Papio Baboon |
| Zdroj: | Journal of Neuroimmunology. 10:255-269 |
| ISSN: | 0165-5728 |
| DOI: | 10.1016/0165-5728(86)90106-2 |
| Popis: | ABH antigens have been demonstrated in the posterior root ganglia (PRG) of 3 primate species (marmoset, baboon and man). Their expression corresponded to the ABO phenotype of the individual and was independent of the secretor gene. In marmosets more cells were positive for H (33 +/- 9%) than for A (19 +/- 6%). In baboons A or B antigens were more easily detected (66 +/- 9%) than the H antigens (48 +/- 5%). In humans more than two-thirds of PRG cells were positive for H but only a small proportion of these were positive for A or B. The ABH antigens were found mainly in the small and intermediate-size neurons whose central processes project to lamina II of the spinal cord posterior horn. Unipolar neurons of the Gasserian ganglion, neurons of the mesencephalic nucleus of the trigeminal nerve and of some visceral ganglia have also been shown to express these antigens which are also present in the fibre layer and glomeruli of the olfactory bulbs. |
| Databáze: | OpenAIRE |
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