Correlative Spectromicroscopy and Tomography for Biomedical Applications Involving Electron, Ion, and Soft X-ray Microscopies

Autor:	Xiaoyue Wang, Neil D. Telling, Kathryn Grandfield, Joanna F. Collingwood, James Everett, Adam P. Hitchcock
Rok vydání:	2019
Předmět:	0303 health sciences Materials science General Computer Science Resolution (electron density) Nanotechnology 02 engineering and technology Scanning transmission X-ray microscopy Q1 021001 nanoscience & nanotechnology R1 Synchrotron law.invention 03 medical and health sciences Electron tomography law Transmission electron microscopy Microscopy Scanning transmission electron microscopy Tomography 0210 nano-technology 030304 developmental biology
Zdroj:	Microscopy Today. 27:12-19
ISSN:	2150-3583 1551-9295
DOI:	10.1017/s1551929518001256
Popis:	Many important scientific and technical problems are best addressed using multiple, microscopy-based analytical techniques that combine the strengths of complementary methods. Here, we provide two examples from biomedical challenges: unravelling the attachment zone between dental implants and bone, and uncovering the mechanism of Alzheimer's disease. They combine synchrotron-based scanning transmission X-ray microscopy (STXM) with transmission electron microscopy ((S)TEM), electron tomography (ET), EELS tomography, and/or atom probe tomography (APT). STXM provides X-ray absorption based chemical sensitivity at mesoscale resolution (10–30 nm), which complements higher spatial resolution electron microscopy and APT.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37301b66b244887be64ebebcaa5d0dd8 https://doi.org/10.1017/s1551929518001256 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.