Unusual Cluster of HIV Type 1 Dual Infections in Groningen, The Netherlands
| Autor: | Tjip S. van der Werf, Marion Cornelissen, Suzanne Jurriaans, Antoinette C. van der Kuyl, Fokla Zorgdrager, Ben Berkhout, Herman G. Sprenger, Nicole K. T. Back |
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| Přispěvatelé: | Amsterdam institute for Infection and Immunity, Medical Microbiology and Infection Prevention |
| Rok vydání: | 2011 |
| Předmět: |
Male
Genotype Immunology Human immunodeficiency virus (HIV) Criminal case HIV Infections medicine.disease_cause Disease cluster SUPERINFECTION Virology REVEALS Cluster Analysis Humans Medicine Men having sex with men Phylogeny Netherlands business.industry env Gene Products Human Immunodeficiency Virus virus diseases Sequence Analysis DNA HIV Reverse Transcriptase Infectious Diseases Sexual abuse Superinfection HIV-1 RNA Viral business |
| Zdroj: | AIDS research and human retroviruses, 27(4), 429-433. Mary Ann Liebert Inc. Aids Research and Human Retroviruses, 27(4), 429-433 |
| ISSN: | 1931-8405 0889-2229 |
| DOI: | 10.1089/aid.2010.0175 |
| Popis: | In 2007, 14 Dutch men having sex with men (MSM) filed a criminal case against three other men, accusing them of administering sedative drugs, sexual abuse, and deliberate subcutaneous injections with HIV-1-infected blood. Medical files showed that 9 of 17 men presented with an acute HIV-1 infection syndrome during 2006–2007. Two men were not infected with HIV. Analysis of viral strains in the 12 MSM and the three alleged donors showed that one donor and six recipients were double infected with two distinct HIV-1 subtype B strains, while another five recipients and one donor were single infected with either strain. Two men were infected with unrelated strains. The finding of multiple double infections with very similar HIV-1 strains is without precedent. |
| Databáze: | OpenAIRE |
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