Characteristics, treatment and outcome of bleeding after tooth extraction in patients on DOAC and phenprocoumon compared to non-anticoagulated patients-a retrospective study of emergency department consultations

Autor: Fabian Schlittler, Aristomenis K. Exadaktylos, Michael Nagler, Martin Müller, Benoit Schaller, Thomas C. Sauter
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Müller, Martin; Schlittler, Fabian; Schaller, Benoît; Nagler, Michael; Exadaktylos, Aristomenis; Sauter, Thomas (2019). Characteristics, treatment and outcome of bleeding after tooth extraction in patients on DOAC and phenprocoumon compared to non-anticoagulated patients-a retrospective study of emergency department consultations. Clinical oral investigations, 23(5), pp. 2273-2278. Springer-Verlag 10.1007/s00784-018-2676-7
DOI: 10.7892/boris.123643
Popis: OBJECTIVES Bleeding after tooth extraction range from minor bleeding to life-threating haemorrhagic shock and are among the leading complications in patients under oral anticoagulation with direct oral anticoagulants (DOACs) or phenprocoumon. Little is known about how anticoagulation in patients under DOAC or phenprocoumon alters the characteristics, treatment or outcome of bleeding events, in comparison to non-anticoagulated patients. METHODS Patients admitted to a tertiary ED in Bern, Switzerland, from June 1st 2012 to 31st May 2016 with bleeding related to tooth extraction under DOAC, phenprocoumon or without anticoagulation, were compared. RESULTS Out of 161,458 emergency consultations, 64 patients with bleeding from tooth extraction were included in our study. In anticoagulation groups, we found significantly more delayed bleeding events than in patients without anticoagulation (9 (81.3%) DOAC, 19 (86.4%) phenprocoumon, 8 (30.8%) no anticoagulation, p
Databáze: OpenAIRE