The 'no-reflow' phenomenon in the coronary arteries
| Autor: | Esteves Filho A, Martinez Filho Ee, Garcia Dp |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1999 |
| Předmět: |
medicine.medical_specialty
lcsh:Diseases of the circulatory (Cardiovascular) system Interventional cardiology Side effect business.industry medicine.medical_treatment medicine.disease Coronary arteries Contrast medium medicine.anatomical_structure Coronary occlusion lcsh:RC666-701 Internal medicine No reflow phenomenon medicine Cardiology Myocardial infarction Cardiology and Cardiovascular Medicine business Cardiac catheterization |
| Zdroj: | Arquivos Brasileiros de Cardiologia, Vol 72, Iss 1, Pp 104-108 (1999) |
| ISSN: | 1678-4170 |
| Popis: | In the last twenty years, the treatment of coronary heart disease with cardiac catheterization has greatly advanced. This therapeutic approach has had unexpected side effects, however, for which solutions must be found, particularly in the are of interventional cardiology. The “noreflow” phenomenon, a side effect, is an uncommon and critical occurrence and, if not reversed, causes a high rate of morbidity and mortality. Its most intriguing clinical characteristic perhaps is its unpredictability. Kloner and co-workers 1 first described the “noreflow” phenomenon in 1974 in dogs with experimentally induced myocardial infarction. The coronary arteries of these dogs were occluded for 40 or 90 minutes, and after that, they were reperfused and studied by means of contrast medium injection. In the coronary arteries occluded for 40 minutes, there was uniform reperfusion of the ischemic myocardium; however, in those occluded for 90 minutes, there was no reperfusion after removal of the coronary occlusion. These investigators concluded that the absence of flow was an ischemic phenomenon, related to the duration of coronary occlusion, which resulted in muscle injury and death of myocardial cells 1 . |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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