Impaired stress-induced pressure natriuresis increases cardiovascularload in African American youths
| Autor: | Delores Gillis, Coral Hanevold, Gaston Kapuku, Lynne Mackey, Martha E. Wilson, Frank A. Treiber, Gregory A. Harshfield |
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| Rok vydání: | 2002 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Black People Natriuresis Blood Pressure Essential hypertension Pressure range Stress Physiological Internal medicine Internal Medicine medicine Humans African american business.industry Stress induced Sodium medicine.disease Endocrinology medicine.anatomical_structure Blood pressure Hypertension Vascular resistance Female Vascular Resistance business Negroid |
| Zdroj: | American journal of hypertension. 15(10 Pt 1) |
| ISSN: | 0895-7061 |
| Popis: | We hypothesized that impaired stress-induced pressure natriuresis increases blood pressure (BP) load.The 118 African American youths were brought into similar levels of sodium balance. The protocol consisted of a 2-h baseline period, a 1-h stress period (competitive video games), and a 2-h recovery period.Normal pressure natriuresis (n = 80) resulted from a resistance-mediated (r = 0.23; P.03) increase in BP (P.001). In contrast, impaired pressure natriuresis (n = 38), leading to an extended period of elevated BP (P.05), resulted from a volume-mediated (r = 0.55; P.002) increase in BP (P.001).Impaired stress-induced pressure natriuresis may contribute to the development of essential hypertension, particularly in African Americans. |
| Databáze: | OpenAIRE |
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