Surgical treatment of gastric cancer invading the oesophagus
| Autor: | L. Bertario, S. Fissi, Federico Bozzetti, P. Bignami, M. Eboli |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
medicine.medical_specialty
Esophageal Neoplasms Linitis plastica medicine.medical_treatment Metastasis Gastrectomy Stomach Neoplasms medicine Humans Neoplasm Invasiveness Thoracotomy Esophagus Lymph node Neoplasm Staging business.industry Cancer General Medicine Middle Aged medicine.disease Prognosis Survival Analysis Surgery medicine.anatomical_structure Oncology Esophagectomy Lymph Node Excision Lymph Nodes business |
| Zdroj: | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. 26(8) |
| ISSN: | 0748-7983 |
| Popis: | There is controversy regarding which type of surgical treatment is most appropriate for upper gastric cancer invading the oesophagus.A review of the pertinent literature was carried out regarding oesophageal involvement in gastric cancer.Invasion of the oesophagus occurred in 26-63% of Western surgical series. It was more frequent in Borrmann IV type, linitis plastica, pT3-pT4, diffuse type by Lauren, N+ or tumours exceeding 5 cm in diameter. Lymphatic tumour spread was caudad (coeliac nodes, hepatoduodenal nodes, paraortic nodes) but mediastinal nodes were also involved if tumour growth in the oesophagus exceeded 3 cm or if there was transmural oesophageal infiltration. In Western countries there was less than 30% 5-year survival and no long-term survivors when hepatoduodenal or mediastinal nodes were metastatic. Mediastinal dissection through thoracotomy did not provide any benefit.A rational approach involves total gastrectomy plus partial oesophagectomy. Abdominal transhiatal resection may be performed in the case of a localized, non-infiltrating tumour and oesophageal involvement2 cm. However, infiltrating, poorly differentiated or Borrmann III-IV tumours require a right thoracotomy to achieve a longer margin of clearance. When oesophageal involvement is3 cm, or hepatoduodenal or mediastinal nodes are positive, no surgical procedure is curative and the literature demonstrates that extended aggressive surgery has no benefits. |
| Databáze: | OpenAIRE |
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