Targeting autophagy in antitumor agent design: furthering the ‘lysosomal love’ strategy
Autor: | Sumit Sahni, Darius J.R. Lane, Patric J. Jansson, Sharleen V. Menezes, Sukriti Krishan, Zaklina Kovacevic, Danuta S. Kalinowski, Michael L.-H. Huang, Des R. Richardson |
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Rok vydání: | 2016 |
Předmět: |
Thiosemicarbazones
0301 basic medicine Antineoplastic Agents Cell Cycle Proteins Biology Bioinformatics Metastasis 03 medical and health sciences Neoplasms Drug Discovery Autophagy Tumor Microenvironment medicine Humans Cell Cycle Protein Pharmacology Antitumor activity Tumor microenvironment Intracellular Signaling Peptides and Proteins Cancer medicine.disease Cancer treatment 030104 developmental biology Drug Design Molecular Medicine Lysosomes |
Zdroj: | Future Medicinal Chemistry. 8:727-729 |
ISSN: | 1756-8927 1756-8919 |
Popis: | The tumor microenvironment has received considerable attention in terms of designing pharmacological strategies for optimising cancer treatment. Considering this, it is notable that the microenvironment of the cancer |
Databáze: | OpenAIRE |
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