The Effects of Simultaneous Pulmonary Rehabilitation during Thoracic Radiotherapy in the Treatment of Malignant Diseases
| Autor: | Won Gu Kim, Sei Won Lee, Hyang Yi Lee, Myeong Geun Choi, Su Ssan Kim, Chang-Min Choi, Seung Hak Lee, Si Yeol Song |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Pulmonary and Respiratory Medicine
Vital capacity medicine.medical_specialty medicine.medical_treatment pulmonary function tests Pulmonary function testing 03 medical and health sciences 0302 clinical medicine medicine Pulmonary rehabilitation 030212 general & internal medicine radiotherapy Pneumonitis lcsh:RC705-779 Lung business.industry lcsh:Diseases of the respiratory system Esophageal cancer medicine.disease pulmonary rehabilitation Miscellaneous Radiation therapy Pneumonia Infectious Diseases medicine.anatomical_structure 030228 respiratory system Original Article Radiology business |
| Zdroj: | Tuberculosis and Respiratory Diseases, Vol 84, Iss 2, Pp 148-158 (2021) Tuberculosis and Respiratory Diseases |
| ISSN: | 2005-6184 1738-3536 |
| Popis: | Background: Radiotherapy is a common treatment option for lung or esophageal cancer, particularly when surgery is not feasible for patients with poor lung function. However, radiotherapy can affect pulmonary function and thereby induce pneumonitis or pneumonia, which can be fatal in patients with respiratory impairment. The purpose of this study is to evaluate if reductions in pulmonary function after radiotherapy can be minimized through simultaneous pulmonary rehabilitation (PR). Methods: In this matched case control study, we retrospectively analyzed patients who had undergone radiotherapy for thoracic malignant disease between January 2018 and June 2019. We analyzed results from pulmonary function tests and 6-minute walking tests (6MWT) conducted within the six months before and after radiotherapy treatment. Results: In total, results from 144 patients were analyzed, with 11 of the patients receiving PR and radiotherapy simultaneously. Of the 133 patients in the control group, 33 were matched with 11 patients in the PR group. Changes in forced expiratory volume in one second (FEV1) and FEV1/forced vital capacity were significantly different between the PR group and the matched control group (240 mL vs. -10 mL, p=0.017 and 5.5% vs. 1.0%, p=0.038, respectively). The median distance of 6MWT in the PR group also increased significantly, from 407.5 m to 493.0 m after radiotherapy (p=0.017). Conclusion: Simultaneous PR improved pulmonary function, particularly in measures of FEV1, and exercise capacity for patients with lung or esophageal cancer even after radiotherapy treatment. These findings may provide an important base of knowledge for further large population studies with long-term follow-up analysis in the identification of the PR’s effects during thoracic radiotherapy. |
| Databáze: | OpenAIRE |
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