Can intraoperative thrombolytic therapy assist with the management of acute limb ischemia?
| Autor: | Ramandeep Sidhu, Anthony J. Comerota |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Embolectomy Risk Assessment Catheterization Intraarterial infusion Graft occlusion Fibrinolytic Agents Ischemia medicine Humans Thrombolytic Therapy Thrombus Thrombectomy Intraoperative Care business.industry Extremities Thrombolysis medicine.disease Limb ischemia Combined Modality Therapy Surgery Radiography Treatment Outcome Treatment modality Acute Disease Cardiology and Cardiovascular Medicine business |
| Zdroj: | Seminars in vascular surgery. 22(1) |
| ISSN: | 1558-4518 |
| Popis: | Catheter-directed thrombolytic therapy is a well-accepted treatment modality for acute arterial and graft occlusion, but intraoperative use of plasminogen activators as an adjunct to operative thrombectomy or thromboembolectomy is frequently overlooked by vascular surgeons. Evidence exists that intraoperative intraarterial infusion of lytic agents is safe and is accompanied by breakdown of distal thrombus. This article describes the rationale for intraoperative thrombolysis, reviews the evidence supporting its use, and suggests several technical approaches to incorporating lytic therapy intraoperatively. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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