Tissue Doppler Imaging (E/e’) and Pulmonary Capillary Wedge Pressure in Patients With Severe Aortic Stenosis
| Autor: | Yoko Kagemoto, Natesa G. Pandian, James D. Thomas, Renan Ferrufino, Jamel Ortoleva, Jeffrey T. Lyvers, Andrew Weintraub, Frederick C. Cobey |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment 030204 cardiovascular system & hematology Doppler imaging Ventricular Function Left Article 03 medical and health sciences 0302 clinical medicine Valve replacement 030202 anesthesiology Internal medicine medicine Humans In patient Pulmonary Wedge Pressure cardiovascular diseases Pulmonary wedge pressure Retrospective Studies Ejection fraction business.industry Pulmonary artery catheter Reproducibility of Results Stroke Volume Retrospective cohort study Aortic Valve Stenosis medicine.disease Echocardiography Doppler Stenosis Anesthesiology and Pain Medicine cardiovascular system Cardiology Cardiology and Cardiovascular Medicine business |
| Zdroj: | J Cardiothorac Vasc Anesth |
| ISSN: | 1053-0770 |
| DOI: | 10.1053/j.jvca.2021.01.051 |
| Popis: | OBJECTIVE: While American and European consensus statements advocate employing the ratio of the transmitral E velocity and tissue Doppler early diastolic mitral annular velocity (E/e’) in the assessment of left heart filling pressures, recent reports have questioned the reliability of this ratio to predict left atrial pressures in a variety of disease states. We hypothesized that there is a clinically significant correlation between E/e’ and pulmonary capillary wedge pressure (PCWP) in patients with severe aortic stenosis. DESIGN: Retrospective cohort study PARTICIPANTS: 733 consecutive patients with severe aortic stenosis who underwent Transcatheter Aortic Valve Replacement (TAVR) for severe aortic stenosis INTERVENTIONS: None MEASUREMENTS AND MAIN RESULTS: PCWP and E/e’(ave) (average of the lateral and medial annulus tissue Doppler velocities) were measured using pulmonary artery catheter and transthoracic echocardiography during pre-procedural evaluation. Patients were grouped by left ventricular ejection fraction (LVEF) ≥ 50% and LVEF < 50%. Spearman rank correlation, anova, t-tests and chi squared tests were used to analyze the data. 79 patients met the inclusion criteria. There was no significant correlation between E/e’(ave) and PCWP (n=79, spearman, r=0.096 p=0.3994). This correlation did not improve when ventricular function was considered (LVEF < 50%: n=11, spearman, r=−0.097, p=0.776; LVEF≥ 50%: n=68, spearman, r=0.116, p=0.345). There was no statistically significant difference in mean PCWP between each range of E/e’(ave). CONCLUSION: We did not find a clinically relevant relationship between E/e’ and PCWP in patients with severe aortic stenosis. |
| Databáze: | OpenAIRE |
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