Identification of sitosteryl glucoside palmitate in a chloroform-derived fraction of Phyllanthus niruri with antiplasmodial and peripheral antinociceptive properties
| Autor: | Kulkarni Roshan, Salawu Oluwakanyinsola Adeola, Joshi Swati, Emeje Martins, Ezenyi Ifeoma Chinwude |
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| Rok vydání: | 2014 |
| Předmět: |
Chloroform
Chromatography Phyllanthus lcsh:Arctic medicine. Tropical medicine biology Silica gel lcsh:RC955-962 Medicinal plant Plasmodium falciparum Fraction (chemistry) biology.organism_classification Biochemistry Genetics and Molecular Biology (miscellaneous) Malaria Hexane chemistry.chemical_compound chemistry Biochemistry Glucoside lcsh:Biology (General) Methanol IC50 lcsh:QH301-705.5 |
| Zdroj: | Asian Pacific Journal of Tropical Biomedicine, Vol 4, Iss 9, Pp 707-713 (2014) |
| ISSN: | 2221-1691 |
| DOI: | 10.12980/apjtb.4.2014apjtb-2013-0025 |
| Popis: | Objective: To evaluate the antiplasmodial properties of fractions of chloroform portion of Phyllanthus niruri (P. niruri) methanol extract and identify a suitable chemical marker present therein. Methods: Chloroform portion of P. niruri methanol extract was separated from silica gel using gradient systems of hexane, ethylacetate and methanol. The fractions were screened for antiplasmodial activity against Plasmodium falciparum HB3 and FcM29. Fractions with IC50 |
| Databáze: | OpenAIRE |
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