| Autor: |
Roberto Alva-Ruiz, Amro M. Abdelrahman, Patrick P. Starlinger, Jennifer A. Yonkus, David N. Moravec, Joel J. Busch, Chad J. Fleming, James C. Andrews, Bernardo C. Mendes, Jill J. Colglazier, Rory L. Smoot, Sean P. Cleary, David M. Nagorney, Michael L. Kendrick, Mark J. Truty |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
HPB. 24:1957-1966 |
| ISSN: |
1365-182X |
| DOI: |
10.1016/j.hpb.2022.06.005 |
| Popis: |
Arterial resection (AR) for pancreatic adenocarcinoma is increasingly considered at specialized centers. We aimed to examine the incidence, risk factors, and outcomes of hepatic artery (HA) occlusion after revascularization.We included patients undergoing HA resection with interposition graft (IG) or primary end-to-end anastomoses (EE). Complete arterial occlusion (CAO) was defined as "early" (EO) or "late" (LO) before/after 90 days respectively. Kaplan-Meier and change-point analysis for CAO was performed.HA resection was performed in 108 patients, IG in 61% (66/108) and EE in 39% (42/108). An equal proportion (50%) underwent HA resection alone or in combination with celiac and/or superior mesenteric artery. CAO was identified in 18% of patients (19/108) with arterial IG least likely to occlude (p=0.019). Hepatic complications occurred in 42% (45/108) and correlated with CAO, symptomatic patients, venous resection, and postoperative portal venous patency. CAO-related operative mortality was 4.6% and significantly higher in EO vs LO (p = 0.046). Median CAO occlusion was 126 days. With change-point analysis, CAO was minimal beyond postoperative day 158.CAO can occur in up to 18% of patients and the first 5-month post-operative period is critical for surveillance. LO is associated with better outcomes compared to EO unless there is inadequate portal venous inflow. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
