Gastric adenocarcinoma of the fundic gland type
| Autor: | Yu-Bo Ren, Xue Fan, Xiang-Chun Lin, Ran-Ran Zeng, Xin Li, Peng Bai, Lei Zhang, Li Wang, Xue-Song Yang, Yan Wang, Yi-Ming Ding |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
China
Pathology medicine.medical_specialty Endoscopic Mucosal Resection Adenocarcinoma 03 medical and health sciences 0302 clinical medicine Pepsinogen A depressed lesion Biopsy medicine Chief cell Humans Endoscopy Digestive System Clinical Case Report 030212 general & internal medicine Mucin-6 Helicobacter pylori medicine.diagnostic_test Esophagogastroduodenoscopy business.industry gastric cancer Stomach Fundic Gland hyperplasia General Medicine Middle Aged Abdominal distension medicine.disease Curvatures of the stomach digestive system diseases medicine.anatomical_structure Gastric Mucosa endoscopic submucosal dissection 030220 oncology & carcinogenesis Female medicine.symptom business Research Article |
| Zdroj: | Medicine |
| ISSN: | 1536-5964 0025-7974 |
| DOI: | 10.1097/md.0000000000020361 |
| Popis: | Introduction: Gastric adenocarcinoma of the fundic gland type (GA-FG) is a newly described entity that is characterized by well-differentiated neoplasm with unclear etiopathogenesis. Patient concerns: A 60-year-old Chinese man was referred to our hospital for abdominal distension. Diagnosis: Esophagogastroduodenoscopy (EGD) showed a depressed lesion found using in the greater curvature of the stomach. The pathological diagnosis of the biopsy specimens indicated that the tumor was GA-FG (chief cell predominant type, GA-FG-CCP). Interventions: Endoscopic submucosal dissection (ESD) was performed. The histopathological examination of the ESD specimen revealed gastric hyperplasia of the fundic gland type around the adenocarcinoma cells. Outcomes: The surgical outcomes were good. The EGD showed a scar with no recurrence, and no symptoms were observed 1 year postoperatively during the follow-up. Conclusion: We present a rare case of a depressed lesion with a pathogenic expression suggesting gastric hyperplasia of the fundic gland type around the adenocarcinoma cells. Considering the origin of oxyntic mucosa, we consider that it may develop into GA-FG. To understand this issue better, similar cases should be monitored in the future. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|