Incidence and Characteristics of Appropriate and Inappropriate Therapies in Recipients of ICD Implanted for Primary Prevention of Sudden Cardiac Death
| Autor: | Fritz Mellert, Jörg Otto Schwab, Georg Nickenig, Bahman Esmailzadeh, Jens Kreuz, R N Nora Liliegren, Osman Balta |
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| Rok vydání: | 2007 |
| Předmět: |
Male
Tachycardia Pediatrics medicine.medical_specialty Ventricular Tachyarrhythmias medicine.medical_treatment Sudden cardiac death Primary prevention medicine Humans In patient Aged Retrospective Studies business.industry Patient Selection Incidence (epidemiology) Retrospective cohort study General Medicine Middle Aged medicine.disease Implantable cardioverter-defibrillator Defibrillators Implantable Death Sudden Cardiac Tachycardia Ventricular Female medicine.symptom Cardiology and Cardiovascular Medicine business |
| Zdroj: | Pacing and Clinical Electrophysiology. 30 |
| ISSN: | 1540-8159 0147-8389 |
| DOI: | 10.1111/j.1540-8159.2007.00621.x |
| Popis: | Background: We evaluated the number of appropriate and inappropriate therapies for ventricular tachyarrhythmias and trigger mechanisms in 55 MADIT II (MII)-like (group 1) and 86 SCD-HeFT-like (group 2) patients. Methods and Results: We analyzed 399 appropriate episodes in 31 patients with implantable cardioverter defibrillators (ICD) implanted according to the MII trial indications, and 502 appropriate episodes in 47 patients matching the SCD-HeFT trial criteria (mean follow-up in both groups = 33 ± 19 months). In group 1, 39 treated episodes were inappropriate (9% of all episodes), while in group 2, 76 episodes were treated inappropriately (15% of all episodes). At least one episode of inappropriate ICD therapy was recorded in 18% of patients in group 1 (n = 10) and in 22% of patients in group 2 (n = 19). Conclusions: Our study supports the implantation of ICD as primary prevention in patients who are at risk of sudden cardiac death, although the proportion of inappropriate ICD interventions remains high. |
| Databáze: | OpenAIRE |
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