Increment of monthly mean predialysis heart rate reflects early cardiac overload in hemodialysis patients with normal cardiac function
| Autor: | Chie Shiraki, Takao Uchida, Masaki Iwasaki, Yuri Tanaka, Hiroki Hase, Yoshihiko Imamura, Nobuhiko Joki, Igor G. Nikolov, Yasunori Takahashi |
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| Rok vydání: | 2010 |
| Předmět: |
Male
Cardiac function curve medicine.medical_specialty medicine.medical_treatment Blood Pressure Cohort Studies Atrial natriuretic peptide Heart Rate Predictive Value of Tests Renal Dialysis Risk Factors Internal medicine Diabetes mellitus Heart rate medicine Humans cardiovascular diseases Prospective cohort study health care economics and organizations Aged Aged 80 and over Heart Failure business.industry Heart Middle Aged medicine.disease Nephrology Heart failure Chronic Disease Disease Progression cardiovascular system Cardiology Female Kidney Diseases Hemodialysis Early phase business human activities Atrial Natriuretic Factor circulatory and respiratory physiology |
| Zdroj: | Journal of Nephrology. 24:185-191 |
| ISSN: | 1121-8428 |
| DOI: | 10.5301/jn.2010.1788 |
| Popis: | BACKGROUND The aim of our study was to examine the association of heart rate (HR) with the onset of congestive heart failure (CHF), and to compare the predictive value of HR with that of the serum level of human atrial natriuretic peptide (hANP) and the cardiothoracic ratio (CTR). METHODS Thirty-eight patients on chronic hemodialysis (HD) aged 68 ± 11 years (61% men, 41% with diabetes) who had normal cardiac function were enrolled in this study. Among them, 6 patients had suffered CHF. Baseline characteristics and HR, hANP and CTR were compared between the 2 groups. RESULTS At baseline, the monthly mean pre-HR (before HD), CTR and hANP values were higher in CHF patients compared with non-CHF patients. In the CHF group, the monthly mean pre-HR increased progressively beginning 10 months before the onset of CHF, which was earlier than the increments of hANP and CTR. A significant difference between the CHF and non-CHF groups was observed earlier for monthly mean pre-HR (4 months before CHF) and ANP (4 months before CHF) than for CTR (2 months before CHF). CONCLUSIONS The increment of monthly mean pre-HR may reflect the early phase of cardiac overload, and is of equal significance to hANP. Further large-scale prospective studies are required to confirm these results. |
| Databáze: | OpenAIRE |
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