Monitoring of patients treated with lithium for bipolar disorder: an international survey
Autor: | Nederlof, M., Heerdink, E.R., Egberts, A.C.G., Wilting, I., Stoker, L.J., Hoekstra, R., Kupka, R.W., Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology |
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Přispěvatelé: | Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Psychiatry, APH - Mental Health |
Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
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Zdroj: | International Journal of Bipolar Disorders, Vol 6, Iss 1, Pp 1-9 (2018) International Journal of Bipolar Disorders International journal of bipolar disorders, 6(1). Springer Open International Journal of Bipolar Disorders, 6(1). SpringerOpen International Journal of Bipolar Disorders, 6(1):12. Springer Open Nederlof, M, Heerdink, E R, Egberts, A C G, Wilting, I, Stoker, L J, Hoekstra, R & Kupka, R W 2018, ' Monitoring of patients treated with lithium for bipolar disorder: an international survey ', International Journal of Bipolar Disorders, vol. 6, no. 1, 12 . https://doi.org/10.1186/s40345-018-0120-1 |
ISSN: | 2194-7511 |
DOI: | 10.1186/s40345-018-0120-1 |
Popis: | Background Adequate monitoring of patients using lithium is needed for optimal dosing and for early identification of patients with (potential) ADEs. The objective was to internationally assess how health care professionals monitor patients treated with lithium for bipolar disorder. Methods Using networks of various professional organizations, an anonymous online survey was conducted among health care professionals prescribing lithium. Target lithium serum levels and frequency of monitoring was assessed together with monitoring of physical and laboratory parameters. Reasons to and not to monitor and use of guidelines and institutional protocols, and local monitoring systems were investigated. Results The survey was completed by 117 health care professionals incorporating responses from twenty-four countries. All prescribers reported to monitor lithium serum levels on a regular basis, with varying target ranges. Almost all (> 97%) monitored thyroid and renal function before start and during maintenance treatment. Reported monitoring of other laboratory and physical parameters was variable. The majority of respondents (74%) used guidelines or institutional protocols for monitoring. In general, the prescriber was responsible for monitoring, had to request every monitoring parameter separately and only a minority of patients was automatically invited. Conclusions Lithium serum levels, renal and thyroid function were monitored by (almost) all physicians. However, there was considerable variation in other monitoring parameters. Our results help to understand why prescribers of lithium monitor patients and what their main reasons are not to monitor patients using lithium. Electronic supplementary material The online version of this article (10.1186/s40345-018-0120-1) contains supplementary material, which is available to authorized users. |
Databáze: | OpenAIRE |
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