Monitoring of patients treated with lithium for bipolar disorder: an international survey

Autor: Nederlof, M., Heerdink, E.R., Egberts, A.C.G., Wilting, I., Stoker, L.J., Hoekstra, R., Kupka, R.W., Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology
Přispěvatelé: Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Psychiatry, APH - Mental Health
Jazyk: angličtina
Rok vydání: 2018
Předmět:
leukocyte count
glomerulus filtration rate
Lithium (medication)
creatinine blood level
Remote patient monitoring
patient monitoring
urinalysis
cholesterol blood level
thyrotropin
thyroxine blood level
0302 clinical medicine
aspartate aminotransferase
Health care
calcium blood level
psychiatrist
resident
030212 general & internal medicine
glucose
kidney function
medical society
Survey
sodium
bipolar disorder
bilirubin blood level
potassium
lcsh:QP351-495
creatinine
article
blood pressure
waist circumference
health survey
very low density lipoprotein
Psychiatry and Mental health
lithium
high density lipoprotein
liver function
nurse practitioner
albumin blood level
Thyroid function
bilirubin
triacylglycerol
medicine.drug
Pregnancy test
medicine.medical_specialty
sodium blood level
Monitoring
Bipolar disorder
alanine aminotransferase
maintenance therapy
urea
electrocardiogram
Lithium
Therapeutic drug monitoring
lcsh:RC321-571
03 medical and health sciences
urea blood level
medicine
parathyroid hormone
human
Medical prescription
lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry
albumin
Biological Psychiatry
thyroxine
potassium blood level
prescription
calcium
business.industry
thyroid function
Research
practice guideline
questionnaire
parathyroid hormone blood level
pregnancy test
lithium blood level
medicine.disease
triacylglycerol blood level
body mass
030227 psychiatry
cell differentiation
pulse rate
glucose blood level
thyrotropin blood level
lcsh:Neurophysiology and neuropsychology
general practitioner
Emergency medicine
high density lipoprotein cholesterol level
Liver function
business
low density lipoprotein
aspartate aminotransferase blood level
clinical protocol
alanine aminotransferase blood level
low density lipoprotein cholesterol level
Zdroj: International Journal of Bipolar Disorders, Vol 6, Iss 1, Pp 1-9 (2018)
International Journal of Bipolar Disorders
International journal of bipolar disorders, 6(1). Springer Open
International Journal of Bipolar Disorders, 6(1). SpringerOpen
International Journal of Bipolar Disorders, 6(1):12. Springer Open
Nederlof, M, Heerdink, E R, Egberts, A C G, Wilting, I, Stoker, L J, Hoekstra, R & Kupka, R W 2018, ' Monitoring of patients treated with lithium for bipolar disorder: an international survey ', International Journal of Bipolar Disorders, vol. 6, no. 1, 12 . https://doi.org/10.1186/s40345-018-0120-1
ISSN: 2194-7511
DOI: 10.1186/s40345-018-0120-1
Popis: Background Adequate monitoring of patients using lithium is needed for optimal dosing and for early identification of patients with (potential) ADEs. The objective was to internationally assess how health care professionals monitor patients treated with lithium for bipolar disorder. Methods Using networks of various professional organizations, an anonymous online survey was conducted among health care professionals prescribing lithium. Target lithium serum levels and frequency of monitoring was assessed together with monitoring of physical and laboratory parameters. Reasons to and not to monitor and use of guidelines and institutional protocols, and local monitoring systems were investigated. Results The survey was completed by 117 health care professionals incorporating responses from twenty-four countries. All prescribers reported to monitor lithium serum levels on a regular basis, with varying target ranges. Almost all (> 97%) monitored thyroid and renal function before start and during maintenance treatment. Reported monitoring of other laboratory and physical parameters was variable. The majority of respondents (74%) used guidelines or institutional protocols for monitoring. In general, the prescriber was responsible for monitoring, had to request every monitoring parameter separately and only a minority of patients was automatically invited. Conclusions Lithium serum levels, renal and thyroid function were monitored by (almost) all physicians. However, there was considerable variation in other monitoring parameters. Our results help to understand why prescribers of lithium monitor patients and what their main reasons are not to monitor patients using lithium. Electronic supplementary material The online version of this article (10.1186/s40345-018-0120-1) contains supplementary material, which is available to authorized users.
Databáze: OpenAIRE
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