Enhancement of phagocytosis and bacterial killing by heterophils from neonatal chicks after administration of Salmonella enteritidis-immune lymphokines

Autor: John R. DeLoach, Lacy L Genovese, Michael H. Kogut, Kenneth J. Genovese, Virginia K. Lowry
Rok vydání: 1999
Předmět:
Zdroj: Veterinary Microbiology. 65:133-143
ISSN: 0378-1135
DOI: 10.1016/s0378-1135(98)00258-2
Popis: During the first week post-hatch, chickens demonstrate an increased susceptibility to infection by bacteria such as Salmonella. The purpose of the present study was to evaluate the effects of immune lymphokines on phagocytosis and killing activities of heterophils in chicks during the first 1–7 days of life. Lymphokines isolated from chicken splenic T-cells harvested from Salmonella enteriditis (SE)-hyperimmunized hens (SE-ILK), have in past experiments, demonstrated augmentation of heterophil activity in day-of-hatch chicks resulting in protection from SE organ invasion. The present experiments reveal significant increases (p
Databáze: OpenAIRE