Reactive oxygen species: Role in carcinogenesis, cancer cell signaling and tumor progression
| Autor: | Fabiola Lilí Sarmiento-Salinas, Adrián Ix-Ballote, Samuel Treviño, Adilene Acosta-Casique, Alfonso Díaz, Paola Maycotte, Nora Hilda Rosas-Murrieta, Andrea Perez-Gonzalez, Lourdes Millan-PerezPeña |
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| Rok vydání: | 2021 |
| Předmět: |
chemistry.chemical_classification
Reactive oxygen species Carcinogenesis Cancer type Cancer General Medicine Biology medicine.disease_cause medicine.disease General Biochemistry Genetics and Molecular Biology chemistry Tumor progression Risk Factors Neoplasms Cancer cell medicine Cancer research Disease Progression Animals Humans General Pharmacology Toxicology and Pharmaceutics Cancer risk Reactive Oxygen Species Signal Transduction |
| Zdroj: | Life sciences. 284 |
| ISSN: | 1879-0631 |
| Popis: | Cancer is one of the major causes of death in the world and its global burden is expected to continue increasing. In several types of cancers, reactive oxygen species (ROS) have been extensively linked to carcinogenesis and cancer progression. However, studies have reported conflicting evidence regarding the role of ROS in cancer, mostly dependent on the cancer type or the step of the tumorigenic process. We review recent studies describing diverse aspects of the interplay of ROS with cancer in the different stages of cancer progression, with a special focus on their role in carcinogenesis, their importance for cancer cell signaling and their relationship to the most prevalent cancer risk factors. |
| Databáze: | OpenAIRE |
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