Renal Resistive Index: Response to Shock and its Determinants in Critically Ill Patients
| Autor: | Jelle L G Haitsma Mulier, Sander Rozemeijer, Heleen M. Oudemans-van Straaten, Pieter R. Tuinman, Angelique M. E. Spoelstra-de Man, Paul W. G. Elbers, Monique C. de Waard, Jantine G Röttgering |
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| Přispěvatelé: | Intensive care medicine, ACS - Diabetes & metabolism, AII - Inflammatory diseases, ACS - Atherosclerosis & ischemic syndromes, ACS - Pulmonary hypertension & thrombosis |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
cardiac index
Male estimated glomerular filtration rate RRI SDF shock 030204 cardiovascular system & hematology Critical Care and Intensive Care Medicine Clinical Science Aspects Doppler ultrasound intensive care unit sidestream dark field HI Cohort Studies Xc 0302 clinical medicine HR eGFR heart rate SIRS Prospective Studies Prospective cohort study interclass correlation coefficient APACHE intensive care pulse pressure index venous oxygen saturation central venous pressure Central venous pressure Acute kidney injury FENa CI Acute Kidney Injury Middle Aged Pulse pressure CVP systemic inflammatory response syndrome predictive mean matching standard error Shock (circulatory) Emergency Medicine Cardiology MAP mean arterial pressure Female medicine.symptom standard deviation Cohort study microvascular flow index medicine.medical_specialty Mean arterial pressure MFI PPI Critical Illness VP perfused vessel density Renal function microcirculation PPV vasopressor fractional excretion of sodium resistance 03 medical and health sciences AKI Internal medicine BIA vessel density bioimpedance medicine Humans proportion of perfused vessels FEUrea SE SD Aged bioelectral impedance analysis PMM business.industry ICC fractional excretion of urea renal resistive index IC 030208 emergency & critical care medicine medicine.disease heterogeneity index PVD VD acute physiology and chronic health evaluation ICU SvO2 bioelectral impedance-derived reactance (membrane capacitance) business human activities |
| Zdroj: | Shock (Augusta, Ga.) Rozemeijer, S, Haitsma Mulier, J L G, Röttgering, J G, Elbers, P W G, Spoelstra-de Man, A M E, Tuinman, P R, de Waard, M C & Oudemans-van Straaten, H M 2019, ' Renal Resistive Index : Response to Shock and its Determinants in Critically Ill Patients ', Shock, vol. 52, no. 1, pp. 43-51 . https://doi.org/10.1097/SHK.0000000000001246 Shock, 52(1), 43-51. Lippincott Williams and Wilkins |
| ISSN: | 1540-0514 1073-2322 |
| Popis: | INTRODUCTION: Shock is characterised by micro- and macrovascular flow impairment contributing to acute kidney injury (AKI). Routine monitoring of the circulation regards the macrocirculation but not the renal circulation which can be assessed with Doppler ultrasound as renal resistive index (RRI). RRI reflects resistance to flow. High RRI predicts persistent AKI. Study aims were to determine whether RRI is elevated in shock and to identify determinants of RRI.MATERIALS AND METHODS: This prospective observational cohort study included two cohorts of patients, with and without shock RESULTS: 92 patients were included (40 shock, 52 non-shock), median age was 69 [60-76] vs. 67 [59-76], p = 0.541; APACHE III was 87 [65-119] vs. 57 [45-69], p CONCLUSIONS: Patients with shock have a higher RRI than patients without. Independent determinants of high RRI were pressure indices of the systemic circulation, low membrane capacitance and pre-admission renal dysfunction. Markers of the sublingual microcirculation were not. TRIAL REGISTRATION CLINICALTRIALS.GOV:: NCT02558166.DATE OF REGISTRATION: 22-09-2015, retrospectively registeredThis is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0. |
| Databáze: | OpenAIRE |
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