Popis: |
The purpose of this paper is to re-emphasize the real and potential dangers of the use of thorotrast as a diagnostic agent. It is hoped by adding to the literature several cases, in which the perivascular injection of thorotrast has produced disabling results, to accentuate the real danger that accompanies its use. Further, we would like to point out the problem of the roentgen diagnosis of thorotrast in the soft tissues when a history of its injection cannot be elicited. Review of Literature An extensive and controversial literature has been built up on the subject of thorotrast since its introduction by Radt in 1929 (15). Excellent reviews have been published by Orr, Popoff et al. (11), Stewart and Ghiselin (19), Yater and Coe (23), and others. Taft (20, 21) has reported volumetric studies on radiation from thorotrast in the tissues and calculated radium equivalents. As a result of his observations, he concluded that the use of 75 c.c. of thorotrast is dangerous, due to the continuous bombardment of the... |