The Curious Case of a Catatonic Patient

Autor: John H. Enterman, Dyllis van Dijk
Rok vydání: 2010
Předmět:
Zdroj: Schizophrenia Bulletin. 37:235-237
ISSN: 1745-1701
0586-7614
Popis: Catatonia is a syndrome characterized by the coexistence of psychiatric and motor symptoms.1 It is associated with a wide range of psychiatric, medical, neurological, and drug-induced disorders.2 The concept of catatonia was first described by the German psychiatrist Kahlbaum in 1874.3 It is more frequently found among patients diagnosed with mania, depression, and neurotoxic syndromes than among those with schizophrenia. Yet, it is mainly classified as a form of schizophrenia.4 The exact cause of catatonia has not been elucidated. The syndrome of catatonia is defined by the objective presence of motor signs, over 40 of which have been described. These catatonic signs are listed in table 1. There is no agreed threshold for the number or duration of symptoms that should be present to justify a diagnosis of catatonia. Research has suffered from this, and studies can rarely be compared with confidence.7 Table 1. Principal Features of Catatonia5,6 There are consistent clinical reports that benzodiazepines are effective in acute catatonia syndromes, particularly stuporous conditions, but no placebo-controlled randomized studies have been published.8,9 However, benzodiazepines are the drugs of choice for catatonia.10 In most cases, lorazepam is administered parenterally or orally beginning with 3 mg/d and increasing rapidly to effective resolution. Dosages of 20–30 mg/d are occasionally necessary.5 Patients who are unresponsive or insufficiently responsive to benzodiazepines need electroconvulsive therapy (ECT).5,10
Databáze: OpenAIRE