Classification of condom lubricants in cyanoacrylate treated fingerprints by desorption electrospray ionization mass spectrometry
| Autor: | Marcel de Puit, Roos Kniest, Mark P.V. Begieneman, Ward van Helmond |
|---|---|
| Přispěvatelé: | Lectoraat Forensisch Onderzoek |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
Spectrometry Mass Electrospray Ionization Materials science Polyethylene glycol Linear discriminant analysis Desorption electrospray ionization mass spectrometry Principal component analysis 01 natural sciences Mass spectrometry imaging Pathology and Forensic Medicine law.invention Condoms 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Condom law Fingerprint Humans Cyanoacrylates 030216 legal & forensic medicine Dermatoglyphics Lubricant Mass Spectrometry Imaging Lubricants Sexual assault Chromatography Polydimethylsiloxane Forensic Sciences 010401 analytical chemistry Discriminant Analysis 0104 chemical sciences chemistry Cyanoacrylate Female Law DESI-MSI |
| Zdroj: | Forensic Science International: an international journal dedicated to the applications of genetics in the administration of justice, 305 Forensic Science International, 305:110005. Elsevier |
| ISSN: | 0379-0738 |
| Popis: | Traces of condom lubricants in fingerprints can be valuable information in cases of sexual assault. Ideally, not only confirmation of the presence of the condom but also determination of the type of condom brand used can be retrieved. Previous studies have shown to be able to retrieve information about the condom brand and type from fingerprints containing lubricants using various analytical techniques. However, in practice fingerprints often appear latent and need to be detected first, which is often achieved by cyanoacrylate fuming. In this study, we developed a desorption electrospray ionization mass spectrometry (DESI-MS) method which, combined with principal component analysis and linear discriminant analysis (PCA-LDA), allows for high accuracy classification of condom brands and types from fingerprints containing condom lubricant traces. The developed method is compatible with cyanoacrylate (CA) fuming. We collected and analyzed a representative dataset for the Netherlands comprising 32 different condoms. Distinctive lubricant components such as polyethylene glycol (PEG), polydimethylsiloxane (PDMS), octoxynol-9 and nonoxynol-9 were readily detected using the DESI-MS method. Based on the analysis of lubricant spots, a 99.0% classification accuracy was achieved. When analyzing lubricant containing fingerprints, an overall accuracy of 90.9% was obtained. Full chemical images could be generated from fingerprints, showing the distribution of lubricant components such as PEG and PDMS throughout the fingerprint, while still allowing for classification. The developed method shows potential for the development of DESI-MS based analyses of CA treated exogenous compounds from fingerprints for use in forensic science. |
| Databáze: | OpenAIRE |
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