Cicatricial pemphigoid: report of five cases
| Autor: | Fabiana Sperandio, S. C. Bohadana, Natasha Braga, Fabrizio Ricci Romano, Aroldo Miniti, Ivan Dieb Miziara |
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| Rok vydání: | 2002 |
| Předmět: |
Larynx
Adult Male Pemphigoid medicine.medical_specialty Pathology Pemphigoid Benign Mucous Membrane Lesion medicine Humans Cicatricial pemphigoid Aged Autoimmune disease integumentary system business.industry Mucous membrane Middle Aged medicine.disease Dermatology eye diseases medicine.anatomical_structure Otorhinolaryngology Histopathology Female medicine.symptom Laryngeal Stenosis business |
| Zdroj: | Ear, nose,throat journal. 81(7) |
| ISSN: | 0145-5613 |
| Popis: | Cicatricial pemphigoid is a chronic, systemic, autoimmune disease characterized by progressive bullous skin and mucous membrane lesions that tend toward scarring and involution. Manifestations of cicatricial pemphigoid include oral mucosal bullous lesions in 85 to 90% of patients, ocular mucosal lesions in 66%, nasal mucosal lesions in 15 to 23%, and laryngeal involvement in 8 to 21 %. We report five cases of cicatricial pemphigoid in which all patients had ENT manifestations—specifically, oral and nasal mucosal involvement. Three of these patients also had laryngeal lesions; one of the three had a large laryngeal ulceration and bullae that caused a laryngeal stenosis and necessitated a tracheostomy. In addition to the five case reports, we also review the literature and discuss the pathogenesis, diagnosis, and treatment of this uncommon disease. |
| Databáze: | OpenAIRE |
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