Radioisotope-dilution curves as an adjunct to cardiac catheterization

Autor: Ramon V. Canent, Aaron P. Sanders, George J. Baylin, Madison S. Spach, John P. Boineau, Alvyn W. White
Rok vydání: 1965
Předmět:
Zdroj: The American Journal of Cardiology. 16:176-183
ISSN: 0002-9149
DOI: 10.1016/0002-9149(65)90471-6
Popis: A method of recordin externally monitored radioisotope-dilution curves at cardiac catheterization has been described. It was found to be reliable and had marked practical value as a routine procedure in the detection and localization of the site of left to right shunts. The geometry of the detection system was defined and correlated with the anatomic structures viewed by the heart and lung probes. Standards for normal curves were established in a series of patients without shunts. Radioisotope curves were compared with arterial dye-dilution curves and blood oxygen data for the detection and localization of the site of left to right shunts. All three methods detected shunts which comprised greater than 25 per cent of total pulmonary blood flow. The isotope and dye methods were found to be equally sensitive in the detection of small shunts if the indicator was injected into the pulmonary artery. All shunts detected by arterial dye-dilution curves were also detected by radioisotope-dilution curves. The reliability of the method was established and its practical usefulness shown. The major advantages of the radioisotope technic without blood sampling were found in severely ill young infants in whom the technic provided a quick and reliable method for the detection and localization of the site of the shunt.
Databáze: OpenAIRE