Ethanol-induced flavor aversions in rats with subdiaphragmatic vagotomies
| Autor: | Stephen W. Kiefer, Rebecca J. Cabral, Kenneth W. Rusiniak, John Garcia |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Male
Taste Gastrointestinal tract Ethanol Physiology medicine.medical_treatment Conditioning Classical Vagus Nerve Pharmacology Vagotomy medicine.disease Extinction Psychological Rats Vagus nerve chemistry.chemical_compound Sensory input chemistry Extinction (neurology) Avoidance Learning medicine Animals Flavor |
| Zdroj: | Behavioral and Neural Biology. 29:246-254 |
| ISSN: | 0163-1047 |
| DOI: | 10.1016/s0163-1047(80)90586-5 |
| Popis: | In two experiments rats with subdiaphragmatic vagotomies were compared to sham-operated rats in the acquisition and extinction of a flavor aversion with ethanol as the illness-inducing agent. Vagotomized rats developed aversions equivalent to those of sham-operated rats whether the ethanol was administered intragastrically (Experiment 1) or intraperitoneally (Experiment 2). Because vagotomy eliminates the majority of sensory input from the gastrointestinal tract, ethanol must exert its aversive effects as a blood-borne toxin rather than as a gastrointestinal irritant. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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