Rates and predictors of adherence and retention for antiretroviral therapy among HIV-positive adults in Enugu, Nigeria
| Autor: | Onyinye Hope Chime, Edmund O. Ndibuagu, Chinonyelu Jennie Orji |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male retention Anti-HIV Agents Enugu State 030231 tropical medicine Psychological intervention Human immunodeficiency virus (HIV) Nigeria HIV Infections medicine.disease_cause Medication Adherence 03 medical and health sciences 0302 clinical medicine Acquired immunodeficiency syndrome (AIDS) Risk Factors Antiretroviral Therapy Highly Active Environmental health Retention in Care Humans Medicine 030212 general & internal medicine Aged Retrospective Studies Original Research Descriptive statistics business.industry PLHIV General Medicine Odds ratio Middle Aged medicine.disease Antiretroviral therapy Confidence interval Cross-Sectional Studies predictors Adherence Female Health education business |
| Zdroj: | Malawi Medical Journal |
| ISSN: | 1995-7262 |
| DOI: | 10.4314/mmj.v31i3.7 |
| Popis: | BackgroundHIV infection and AIDS are majorpublic health challenges in Nigeria, a country with one of the highest rates of new infection in sub-Saharan Africa and the second largest HIV epidemic in the world.Non-adherence to medication and defaulting from treatment are the two major challenges faced by anti-retroviral therapy (ART) programs in resource-constrained settings. This study was undertaken to determine the rate and predictors of adherence to medication and retention among people living with HIVin Enugu State, Nigeria.MethodsThis was a cross-sectionalretrospective study conducted among adults living with HIV(PLHIV) receiving ARTs in eightcomprehensive health facilities in Enugu, Nigeria. We used self-reported adherence and recorded clinic visits to assess adherence and retention, respectively. Descriptive statistics (frequencies, proportions, mean and standard deviation) and regression analysis were then conducted to identify the association between adherence, retention and demographic and health-related factors. ResultsThe mean age of respondents was 38.5±9.8 years. Predictors of good adherence to medication includedbeing male(adjusted odds ratio [AOR]:2.08; 95% confidence interval [CI]:1.12–3.85), having been on anti-retroviral medications for more than 5 years (AOR:1.92; 95% CI: 1.17–3.16), the non-consumption of alcohol(AOR: 3.67; 95% CI: 2.01–6.70),not usingtraditional medicine (AOR: 2.76; 95% CI:1.33–5.73) and having a baseline CD4count exceeding 500 cells/μl (AOR: 5.67; 95% CI: 1.32–24.32).Adequate retention was predicted by being resident in the urban area (AOR: 1.90; 95% CI: 1.17–3.06). Being away from home (41.8%) and forgetfulness (35.0%) were reported as the major reasons for missing medication.ConclusionThe rates of adherence and retention found in this study were similar to those reported forother resource-limited settings. Health education and behavioural modification interventions should be intensified to reduce the consumption of alcohol and the use of traditional medicine by people living with HIV. Identifying other factors may help to design effective strategies to ensure that people living with HIV adhere to their medications and remain in care. |
| Databáze: | OpenAIRE |
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