Metastatic Malignant Blue Nevus
Autor: | A Gököz, I Barişta, Aycan Kayikçioğlu, Mustafa Akyürek, Figen Özgür |
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Rok vydání: | 1997 |
Předmět: |
Pathology
medicine.medical_specialty Lung Neoplasms Skin Neoplasms Nodular melanoma Metastasis Fatal Outcome Nevus Blue medicine Humans Nevus skin and connective tissue diseases Blue nevus business.industry Melanoma Liver Neoplasms Cellular Blue Nevus Middle Aged medicine.disease Lymphatic Metastasis Arm Female Surgery Histopathology Lymph Nodes Differential diagnosis medicine.symptom Tomography X-Ray Computed business |
Zdroj: | Annals of Plastic Surgery. 39:411-415 |
ISSN: | 0148-7043 |
DOI: | 10.1097/00000637-199710000-00012 |
Popis: | This report presents a 63-year-old Caucasian woman with a malignant blue nevus, which is an extremely rare form of melanoma originating from or associated with a preexisting blue nevus. The background blue nevus on the left upper arm, which had been present for 5 to 6 years, increased in size and darkened in color for 3 months prior to histological diagnosis of malignant blue nevus. Although the tumor looked much like a nodular melanoma clinically, the diagnosis of malignant blue nevus was established histologically. The patient had a poor outcome due to metastatic spread of the tumor to the visceral organs 1 year following the initial excision of the tumor. To distinguish this rare tumor from other melanocytic lesions, strict histological criteria are needed to make the diagnosis of malignant blue nevus. Differential diagnosis includes cellular blue nevus, atypical cellular blue nevus, primary malignant melanoma, and metastatic melanoma to the dermis. Malignant blue nevus is most commonly seen on the scalp. The tumor has an aggressive behavior and metastasizes in the majority of patients. This paper describes the second reported case of malignant blue nevus involving the upper arm. Clinical and histological features of this uncommon tumor are presented, along with a review of the literature. |
Databáze: | OpenAIRE |
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