SOFA score is superior to APACHE-II score in predicting the prognosis of critically ill patients with acute kidney injury undergoing continuous renal replacement therapy

Autor: Jiangli Sun, Yu Shi, Hong Hong Pei, Zheng-Hai Bai, Hai Wang, Xiao Kang, Jun-Hua Lv
Rok vydání: 2020
Předmět:
Adult
Male
China
medicine.medical_specialty
Time Factors
Continuous Renal Replacement Therapy
Organ Dysfunction Scores
Critical Illness
medicine.medical_treatment
030232 urology & nephrology
Apache II score
030204 cardiovascular system & hematology
lcsh:RC870-923
Critical Care and Intensive Care Medicine
Risk Assessment
APACHE-II score
03 medical and health sciences
0302 clinical medicine
Predictive Value of Tests
Risk Factors
Internal medicine
parasitic diseases
medicine
Humans
Renal replacement therapy
SOFA score
APACHE
Aged
Retrospective Studies
urogenital system
business.industry
Critically ill
Acute kidney injury
General Medicine
Acute Kidney Injury
Middle Aged
lcsh:Diseases of the genitourinary system. Urology
Prognosis
medicine.disease
Intensive Care Units
Logistic Models
Nephrology
Multivariate Analysis
Clinical Study
Female
Multiple organ dysfunction syndrome
business
Research Article
Zdroj: Renal Failure
article-version (VoR) Version of Record
Renal Failure, Vol 42, Iss 1, Pp 638-645 (2020)
ISSN: 1525-6049
0886-022X
DOI: 10.1080/0886022x.2020.1788581
Popis: Background Acute kidney injury (AKI) is the most common cause of organ failure in multiple organ dysfunction syndrome (MODS) and is associated with increased mortality. This study aimed at determining the efficacy of sequential organ failure assessment (SOFA), and acute physiology and chronic health evaluation II (APACHE-II) scoring systems in assessing the prognosis of critically ill patients with AKI undergoing continuous renal replacement therapy (CRRT). At present, APACHE-II score and SOFA score were also used to evaluate and predict the prognosis of critically ill patients with AKI. Methods The predictive value of SOFA and APACHE-II scores for 28- and 90-d mortality in patients with AKI undergoing CRRT were determined by multivariate analysis, sensitivity analysis, and curve-fitting analysis. Results A total of 836 cases were included in this study. Multivariate Cox logistic regression analysis showed that SOFA scores were associated with 28- and 90-d mortality in patients with AKI undergoing CRRT. The adjusted HR of SOFA for 28-d mortality were 1.18 (1.14, 1.21), 1.24 (1.18, 1.31), and 1.19 (1.13, 1.24) in the three models, respectively, and the adjusted HR of SOFA for 90-d mortality was 1.12 (1.09, 1.16), 1.15 (1.10, 1.19), and 1.15 (1.10, 1.19), respectively. The subgroup analysis showed that the SOFA score was associated with 28-d and 90-d mortality in patients with AKI undergoing CRRT. APACHE-II score was not associated with 28- and 90-d mortality patients with AKI undergoing CRRT. Curve fitting analysis showed that SOFA scores increased had a higher prediction accuracy for 28- and 90-d than APACHE-II. Conclusions The SOFA score showed a higher accuracy of mortality prediction in critically ill patients with AKI undergoing CRRT than the APACHE-II score.
Databáze: OpenAIRE
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