Glutathione S-Transferase Activity in Human Fetal and Adult Tissues
| Autor: | Douwe D. Breimer, Juul Th. Wijnen, Hasan Mukhtar, Clema E.M. Zoetemelk, A.J. Baars, Meera Khan, Lucie M.M. Blankenstein-Wijnen |
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| Rok vydání: | 1981 |
| Předmět: |
Adult
Male medicine.medical_specialty Gestational Age Biology GPX5 chemistry.chemical_compound Fetus Internal medicine medicine Humans Tissue Distribution Glutathione Transferase Pharmacology Kidney Stomach Infant Newborn General Medicine Glutathione Middle Aged Enzyme assay Endocrinology medicine.anatomical_structure Glutathione S-transferase chemistry biology.protein Female Drug metabolism |
| Zdroj: | Pharmacology. 22:322-329 |
| ISSN: | 1423-0313 0031-7012 |
| Popis: | Quantitative estimations of glutathione S-transferase activities with 1-chloro-2,4-dinitrobenzene as the electrophilic second substrate, in 142 postmortem human tissue specimens derived from 34 different organs of one or more of 13 individuals belonging to various age groups, are presented. Collectively the data indicate: (1) all tissues examined have appreciable levels of enzyme activity; (2) liver, kidney, lung, muscle, heart, adrenal glands, pancreas, and stomach of fetal origin possess higher enzyme activities than those of the adults, and (3) there are wide interindividual variations in the tissue enzyme activities. |
| Databáze: | OpenAIRE |
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