Current Paediatric Coeliac Disease Screening Strategies and Relevance of Questionnaire Survey
| Autor: | Lyudmila V. Savvateeva, Svetlana I. Erdes, Andrey A. Zamyatnin, Anton S. Antishin |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Pediatrics
medicine.medical_specialty Adolescent Glutens Immunology Autoimmunity Disease Autoimmune enteropathy Asymptomatic Autoantigens Coeliac disease 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Surveys and Questionnaires Immunology and Allergy Relevance (law) Medicine Humans Mass Screening Child Mass screening business.industry Questionnaire General Medicine medicine.disease Celiac Disease Early Diagnosis 030211 gastroenterology & hepatology medicine.symptom business Paediatric population |
| Zdroj: | International archives of allergy and immunology. 177(4) |
| ISSN: | 1423-0097 |
| Popis: | Coeliac disease (CD) is an autoimmune enteropathy triggered by the ingestion of gluten-containing grains in genetically predisposed individuals. Identification of CD in clinical practice is often difficult due to the manifestation of non-specific symptoms and signs, so a relatively significant proportion of CD cases remain undiagnosed. Timely detection of the disease is necessary to provide an appropriate approach to control of the disease treatment, in order to avoid potential complications. This is even more important in the case of children and adolescents, to ensure their proper growth and development. In this review, we discuss the data on the current strategies for CD detection among paediatric populations and the role of questionnaire-based discovery of CD cases in the area of interest. We assume that mass screening is a preferable strategy for finding CD cases within the paediatric population because this could uncover symptomatic, oligosymptomatic, and asymptomatic CD cases. However, under conditions of limited financial resources, screening for CD in risk groups, members of which can be identified using questionnaires, is essential. The pros and cons of CD screening in paediatric populations are presented. These depend on a number of situational criteria (cost-effectiveness, lack of awareness), but screening is designed to improve the detection of the disease and therefore improve the quality of life of patients. |
| Databáze: | OpenAIRE |
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