Nonsteroidal anti-inflammatory drugs and antihypertensives: how do they relate?
| Autor: | Isabel Moreno-Hay, Zovinar Der Khatchadourian, Reny de Leeuw |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
musculoskeletal diseases
Drug medicine.medical_specialty medicine.drug_class media_common.quotation_subject Disease Pharmacology digestive system Anti-inflammatory Pathology and Forensic Medicine chemistry.chemical_compound Risk Factors Internal medicine medicine Humans Drug Interactions Radiology Nuclear Medicine and imaging Dentistry (miscellaneous) In patient skin and connective tissue diseases Antihypertensive Agents media_common Nonsteroidal business.industry Anti-Inflammatory Agents Non-Steroidal digestive system diseases chemistry Concomitant Healthy individuals Surgery Oral Surgery business |
| Zdroj: | Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 117:697-703 |
| ISSN: | 2212-4403 |
| Popis: | Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely available as over-the-counter medications, despite their numerous side effects and drug interactions. The aim of this article is to increase awareness of the hypertensive potential of NSAIDs and their interference with antihypertensives. Patients with hypertension appear to be more susceptible than normotensive individuals to the blood pressure-increasing effect of NSAIDs. Most studies have found that short-term use of NSAIDs does not pose a major risk for hypertension or increase in cardiovascular disease in healthy individuals. The calcium channel blockers and β-blockers seem to be least affected by the concomitant use of NSAIDs. A dentist must weigh the benefits and disadvantages of using NSAIDs in patients taking antihypertensive drugs. For those who may be at greater risk, such as patients with hypertension and the elderly, careful selection of the class of NSAID and close monitoring are appropriate measures, especially if long-term use is anticipated. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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