Photodynamic therapy fortified with topical oleyl alcohol-based transethosomal 8-methoxypsoralen for ameliorating vitiligo: Optimization and clinical study

Autor: Dina B, Mahmoud, Aliaa N, ElMeshad, Maha, Fadel, Abeer, Tawfik, Shahenda A, Ramez
Rok vydání: 2022
Předmět:
Zdroj: International Journal of Pharmaceutics. 614:121459
ISSN: 0378-5173
DOI: 10.1016/j.ijpharm.2022.121459
Popis: Vitiligo is a common autoimmune skin disorder that is characterized by patchy depigmentation of the skin due to melanocytes and melanin loss. Herein, photodynamic therapy mediated 8-methoxypsoralen (8-MOP), has been used fortified with topical oleyl alcohol-based transethosomes; to overcome the poor solubility and adverse effects associated with 8-MOP oral delivery. A 2
Databáze: OpenAIRE