Reorganization of visual fields after periventricular haemorrhagic infarction: potentials and limitations

Autor: Simona Fiori, Andrea Guzzetta, Eugenia Conti, Danilo Scelfo, Ada Bancale
Rok vydání: 2013
Předmět:
Brain Infarction
genetic structures
Thalamus
Vision Disorders
Infarction
Diseases
Infant
Premature
Diseases
Basal Ganglia
Lesion
Developmental Neuroscience
Neuroplasticity
Basal ganglia
medicine
Humans
Premature
Neuronal Plasticity
medicine.diagnostic_test
business.industry
physiopathology
Brain Infarction
complications/physiopathology
Humans
Infant
Infant
Premature
Infant
etiology/physiopathology
Intracranial Hemorrhages
complications/physiopathology
Neuronal Plasticity
physiology
Thalamus
physiopathology
Vision Disorders
etiology/physiopathology
Visual Fields
physiology
Infant
Magnetic resonance imaging
complications/physiopathology
medicine.disease
etiology/physiopathology
eye diseases
Visual field
Pediatrics
Perinatology and Child Health
Neurology (clinical)
physiopathology
Visual Fields
medicine.symptom
business
Intracranial Hemorrhages
Neuroscience
Infant
Premature
Tractography
Zdroj: Developmental Medicine & Child Neurology. 55:23-26
ISSN: 0012-1622
DOI: 10.1111/dmcn.12302
Popis: Visual functions are often impaired in preterm infants with periventricular haemorrhagic infarction, because of the involvement of the region where the optic radiations are located. In some cases an unexpected sparing of the visual fields has been described, and related to the plasticity of thalamo-cortical afferents that are supposedly able to bypass the lesion when it occurs in the early third trimester of gestation. We systematically reviewed the literature in the field to determine the limits and potentials of this type of reorganization. We found four studies meeting our criteria, from which we extracted case reports on 19 individuals with intraventricular haemorrhagic infarction. Eleven of the 19 did not have visual field defects, five had a bilateral visual field defect, and the remaining three had a unilateral visual field defect. The involvement of the optic radiations was often associated with normal visual fields as only one of the four individuals with damaged optic radiations showed visual field defects. Conversely, the presence of basal ganglia/thalamus involvement apparently prevented such reorganization, as the only two individuals with unilateral field restriction and available magnetic resonance imaging data both showed abnormalities in those structures. Consistent with this, we report on a further individual in which visual field restriction was associated with abnormal tractography on brain magnetic resonance imaging. Overall, this review supports the existence of effective mechanisms of plastic reorganization that allow a rewiring of geniculo-calcarine connections with restoration of full field vision but which are hindered by the involvement of the basal ganglia and thalamus.
Databáze: OpenAIRE
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