Prognostic value of heparin-binding protein for mortality in severe COVID-19 pneumonia

Autor:	Tarık Acar, Birsen Ertekin, Mehmet Yortanlı, Sedat Koçak
Rok vydání:	2022
Předmět:	Biochemistry (medical) Clinical Biochemistry Drug Discovery COVID-19 Humans Blood Proteins Prognosis Biomarkers Antimicrobial Cationic Peptides
Zdroj:	Biomarkers in Medicine. 16:981-991
ISSN:	1752-0371 1752-0363
Popis:	Aim: The study investigated heparin-binding protein (HBP) levels in patients with severe COVID-19 pneumonia and their relation to prognosis. Methods: A total of 134 patients with serious COVID-19 pneumonia were prospectively analyzed. HBP levels were statistically compared between both the patient and healthy control groups and within the patient group itself. Results: HBP was defined to be significantly higher in the patient group compared with the control group. There was a statistically significant distinction between the patients who survived and those who died with regard to HBP levels. When the cutoff value of HBP was >13.47, sensitivity (89.8%), specificity (74.1%) had area under the curve values of 0.806 (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3637e638fde8e326f8f3e53e6a5ea653 https://doi.org/10.2217/bmm-2022-0265 Zobrazit plný text záznamu