Antenna Design and SAR Analysis on Human Head Phantom Simulation for Future Clinical Applications
| Autor: | Jorge J. Morisaki, Seshasai Vamsi Krishna Peddinti, James Rizkalla, Felipe P. Perez, Maher Rizkalla, Paul Salama, Joseph Paul Bandeira |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Electromagnetic field Human head Computer science Multiphysics Acoustics Specific absorption rate Linearity Imaging phantom Article 03 medical and health sciences COMSOL 030104 developmental biology 0302 clinical medicine Antenna Alzheimer Disease Diagnosis Antenna (radio) Neuro Driven element 030217 neurology & neurosurgery Simulation SAR |
| Zdroj: | Journal of biomedical science and engineering |
| ISSN: | 1937-6871 |
| Popis: | Background: The rapid development of a variety of devices that emit Radiofrequency Electromagnetic fields (RF-EMF) has sparked growing interest in their interaction with biological systems and the beneficial effects on human health. As a result, investigations have been driven by the potential for therapeutic applications, as well as concern for any possible negative health implications of these EM energies [1-4]. Recent results have indicated specific tuning of experimental and clinical RF exposure may lead to their clinical application toward beneficial health outcomes [5]. Method: In the current study, a mathematical and computer simulation model to analyze a specific RF-EMF exposure on a human head model was developed. Impetus for this research was derived from results of our previous experiments which revealed that Repeated Electromagnetic Field Stimulation (REMFS) decreased the toxic levels of beta amyloid (Aβ) in neuronal cells, thereby suggesting a new potential therapeutic strategy for the treatment of Alzheimer’s disease (AD). Throughout development of the proposed device, experimental variables such as the EM frequency range, specific absorption rate (SAR), penetration depth, and innate properties of different tissues have been carefully considered. Results: RF-EMF exposure to the human head phantom was performed utilizing a Yagi-Uda antenna type possessing high gain (in the order of 10 dbs) at a frequency of 64 MHz and SAR of 0.6 W/Kg. In order to maximize the EM power transmission in one direction, directors were placed in front of the driven element and reflectors were placed behind the driven element. So as to strategically direct the EM field into the center of the brain tissue, while providing field linearity, our analysis considered the field distribution for one versus four antennas. Within the provided dimensions of a typical human brain, results of the Bioheat equation within COMSOL Multiphysics version 5.2a software demonstrated less than a 1 m°K increase from the absorbed EM power. |
| Databáze: | OpenAIRE |
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