Event-related and readiness potentials when preparing to approach and avoid alcohol cues following cue avoidance training in heavy drinkers
| Autor: | Andrej Stancak, Vicente Soto, Matt Field, Nicholas Fallon, Lisa C. G. Di Lemma |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Cognitive bias modification medicine.medical_specialty Alcohol Drinking Contingent Negative Variation Alcohol Audiology Electroencephalography 050105 experimental psychology Motor readiness potentials Random Allocation Young Adult 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Event-related potential Intervention (counseling) Avoidance Learning Reaction Time medicine Humans Attention 0501 psychology and cognitive sciences Evoked Potentials Original Investigation Event (probability theory) Pharmacology Readiness Potentials Heavy drinking medicine.diagnostic_test 05 social sciences Avoidance training Event related potentials chemistry Female Cues Psychology Photic Stimulation 030217 neurology & neurosurgery |
| Zdroj: | Psychopharmacology |
| ISSN: | 1432-2072 0033-3158 |
| DOI: | 10.1007/s00213-020-05462-7 |
| Popis: | Rationale Cue avoidance training (CAT) reduces alcohol consumption in the laboratory. However, the neural mechanisms that underlie the effects of this intervention are poorly understood. Objectives The present study investigated the effects of a single session of CAT on event-related and readiness potentials during preparation of approach and avoidance movements to alcohol cues. Methods Heavy drinking young adults (N = 60) were randomly assigned to complete either CAT or control training. After training, we recorded participants’ event-related and motor readiness potentials as they were preparing to respond. Results In the CAT group, N200 amplitude was higher when preparing to approach rather than avoid alcohol pictures. In the control group, N200 amplitudes did not differ for approach and avoidance to alcohol pictures. Regarding the late positive potential (LPP), in the CAT group, the negativity of this was blunted when preparing to avoid alcohol pictures relative to when preparing to avoid control pictures. In the control group, the negativity of the LPP was blunted when preparing to approach alcohol pictures relative to when preparing to approach control pictures. There were no effects on motor readiness potentials. Behavioural effects indicated short-lived effects of training on reaction times during the training block that did not persist when participants were given time to prepare their motor response before executing it during the EEG testing block. Conclusions After a single session of CAT, the enhanced N200 when approaching alcohol cues may indicate the engagement of executive control to overcome the associations learned during training. These findings clarify the neural mechanisms that may underlie the effects of CAT on drinking behaviour. |
| Databáze: | OpenAIRE |
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