Quality of Life and Psychological Disorders in Coeliac Disease: A Prospective Multicentre Study
| Autor: | Fabiana Zingone, Valerio Zorzetto, Isabella Rosato, Ilaria Marsilio, Anna D'Odorico, Giovanni Cataudella, Cristina Canova, Flavio Valiante |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Affect (psychology) Article Coeliac disease Diet Gluten-Free Anxiety Celiac disease Depression Dietary compliance Quality of life Surveys and Questionnaires Humans Medicine TX341-641 In patient Prospective cohort study Depression (differential diagnoses) Nutrition and Dietetics Nutrition. Foods and food supply business.industry dietary compliance anxiety medicine.disease Anxiety Disorders quality of life Mood disorders depression Patient Compliance Female medicine.symptom business celiac disease Food Science |
| Zdroj: | Nutrients, Vol 13, Iss 3233, p 3233 (2021) Nutrients Volume 13 Issue 9 |
| ISSN: | 2072-6643 |
| Popis: | Coeliac disease (CeD) has been associated with psychological disorders and reduced quality of life. Our prospective study evaluated the changes in the quality of life, anxiety and depression in CeD patients up to two years after diagnosis. We recruited adult patients residing in the Veneto region with a new diagnosis of CeD. Several validated questionnaires were administered to measure quality of life, psychological symptoms and adherence to a gluten-free diet (GFD) at the time of diagnosis and after 1 and 2 years. Ninety-three patients reached the 1-year follow-up (81.7% were females with a median age at diagnosis of 35 years), and 55 patients reached the 2-year follow-up. We observed a significant improvement in quality of life, anxiety and depression scores at 1 year after diagnosis, particularly in patients who complied with a GFD. The improvements among classical CeD patients were similar to those observed in nonclassical patients except for anxiety, which improved only in patients with a classical presentation at diagnosis. Age, sex and other disease factors did not affect the change in quality of life (QoL) or other mood disorders. Most of the improvements measured 1 year after diagnosis and 2 years after diagnosis were not significant. In conclusion, QoL and mood disorders must be considered, and psychological counselling should be used when needed. |
| Databáze: | OpenAIRE |
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