Ott's protein osmotic pressure of serum and interstitial fluid in chickens (Gallus gallus): effect of age and gender
| Autor: | Satu Sankari, Liisa M. Peltonen |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Male
Oncotic pressure medicine.medical_specialty Physiology 030204 cardiovascular system & hematology Aquatic Science Models Biological 03 medical and health sciences Sex Factors 0302 clinical medicine Interstitial matrix Osmotic Pressure Interstitial fluid Internal medicine Extracellular fluid Starling equation medicine Animals Osmotic pressure Molecular Biology Ecology Evolution Behavior and Systematics 030304 developmental biology Analysis of Variance 0303 health sciences Chemistry Age Factors Albumin Extracellular Fluid Blood Proteins Capillaries Suction blister Endocrinology Hematocrit Insect Science Female Animal Science and Zoology Rheology Chickens |
| Zdroj: | Journal of Experimental Biology. 214:599-606 |
| ISSN: | 1477-9145 0022-0949 |
| DOI: | 10.1242/jeb.048769 |
| Popis: | Protein, or colloid, osmotic pressure (COP) is of sufficient magnitude to exert a powerful effect on Starling forces across the capillary wall. Although avian skin lacks active mechanisms for fluid transmission, such as sweating, it is now hypothesized that passive oncotic forces may regulate fluid flow and distribution in the skin and related phenomena. In this study, serum protein profiles, as well as COP in serum (COPs) and in suction blister fluid (COPsbf), were determined in juvenile, young and adult female and male chickens. For assessing COP, the Ott-Ahlqvist equation was applied. This equation can formulate the effects of multiple serum proteins on COP, according to their molecular mass. The COP values determined in chickens were lower than those previously found in mammals. COPs increased with age in males, and was higher in adult males than in adult females. In contrast, COPsbf decreased with age in females, although it was better preserved in adult males. The age-dependent decrease in COP was associated with a parallel decrease in the concentration of α1-globulin and albumin, and a positive correlation between packed cell volume (PCV) and COP was found. It is concluded that ageing affects Ott's COP around the vessel wall, and that an oncotic mechanism preserves plasma volume. The preservation of COPsbf in males suggests better maintenance of the interstitial ground substance. Females seem to lose more of a tissue's COPs counteracting force than males, probably as a result of gender-specific changes in the composition of the interstitial matrix. Further studies are required to elucidate the structure and function of avian lymphatics and their role in skin rheology. * COPOtt : Ott's colloid osmotic pressure (Ott's protein osmotic pressure) COPs : colloid osmotic pressure of serum COPsbf : colloid osmotic pressure of suction blister fluid ECF : extracellular fluid GAG : glycosaminoglycan IF : interstitial fluid PCV : packed cell volume SBF : suction blister fluid TPR : total protein |
| Databáze: | OpenAIRE |
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