The laminin family
| Autor: | Monique Aumailley |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Protein Folding
Protein Conformation Integrin Review Basement Membrane Receptors Laminin Cellular and Molecular Neuroscience Protein structure Laminin Protein Interaction Mapping Cell Adhesion Extracellular Animals Humans Cell adhesion chemistry.chemical_classification Binding Sites biology Cell Biology Extracellular Matrix Protein Structure Tertiary Cell biology Molecular Weight chemistry biology.protein Protein folding Glycoprotein Cell Adhesion Molecules Intracellular Signal Transduction |
| Zdroj: | Cell Adhesion & Migration. 7:48-55 |
| ISSN: | 1933-6926 1933-6918 |
| Popis: | Laminins are large molecular weight glycoproteins constituted by the assembly of three disulfide-linked polypeptides, the α, β and γ chains. The human genome encodes 11 genetically distinct laminin chains. Structurally, laminin chains differ by the number, size and organization of a few constitutive domains, endowing the various members of the laminin family with common and unique important functions. In particular, laminins are indispensable building blocks for cellular networks physically bridging the intracellular and extracellular compartments and relaying signals critical for cellular behavior, and for extracellular polymers determining the architecture and the physiology of basement membranes. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|