Intestinal barrier and mucosal immunity in broilers, Thai Betong, and native Thai Praduhangdum chickens
| Autor: | Chaiwat Boonkaewwan, Autchara Kayan, Nunyarat Koomkrong, Sirin Theerawatanasirikul |
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| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Pathology animal structures 040301 veterinary sciences Ileum Biology Intestinal morphology digestive system Gastroenterology Chicken intestinal barrier intestinal morphology mucosal immunity tight junction 0403 veterinary science Intestinal mucosa Immunity Internal medicine medicine Veteriner Hekimlik Mucosal immunity General Veterinary Tight junction 0402 animal and dairy science Histology 04 agricultural and veterinary sciences 040201 dairy & animal science Veterinary medicine.anatomical_structure Duodenum |
| Zdroj: | Volume: 41, Issue: 3 357-364 Turkish Journal of Veterinary and Animal Sciences |
| ISSN: | 1303-6181 1300-0128 |
| DOI: | 10.3906/vet-1609-58 |
| Popis: | The intestinal barrier includes physical and chemical components for preventing the invasion of pathogenic and toxic agents. The aim of this study was to investigate small intestinal morphology, antimicrobial peptides, and tight junction (TJ) distribution among broilers, Thai Betong chickens, and native Thai Praduhangdum chickens. Intestinal samples from 40 chickens of each breed were collected. The results of the histological and morphological examination revealed that the duodenum of all breeds had the maximum villus height compared to the other parts. The intestinal tract of both Betong and Praduhangdum chickens was low in the number of mucin and goblet cells. In broilers, the intestinal surface mucins correlated with the number of β-defensin-positive Paneth cells. Claudin-1 protein was observed in the cytoplasm of the epithelium in all breeds, with the highest intensity of claudin-1 staining detected in the intestinal cells of the ileum. Localization of occludin was higher in the broilers in all intestinal segments than in the native Thai chickens. In conclusion, the broilers exhibited a large amount of TJ proteins and mucosal immunity as compared to native Thai-breed chickens. TJ localizations together with intestinal morphology and mucosal immunity can be utilized as biological markers for gut health. |
| Databáze: | OpenAIRE |
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