Inflammatory Diseases of the Central Nervous System
Autor: | Eyal Muscal, Timothy Lotze, Nikita Shukla |
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Rok vydání: | 2021 |
Předmět: |
Central Nervous System
medicine.medical_specialty Movement disorders Encephalopathy Central nervous system Cns vasculitis Bioinformatics 03 medical and health sciences 0302 clinical medicine Central Nervous System Diseases Epidemiology medicine Humans 030212 general & internal medicine Child Vasculitis Central Nervous System Inflammation Brain Diseases Epilepsy business.industry Mechanism (biology) Neurodegenerative Diseases medicine.disease Pathophysiology medicine.anatomical_structure Neurology (clinical) medicine.symptom Focal neurologic deficits business 030217 neurology & neurosurgery |
Zdroj: | Neurologic clinics. 39(3) |
ISSN: | 1557-9875 |
Popis: | Pediatric neuroinflammatory conditions are a complex group of disorders with a wide range of clinical presentations. Patients can present with a combination of focal neurologic deficits, encephalopathy, seizures, movement disorders, or psychiatric manifestations. There are several ways that pediatric neuroinflammatory conditions can be classified, including clinical presentation, pathophysiologic mechanism, and imaging and laboratory findings. In this article, we group these conditions into acquired demyelinating diseases, immune-mediated epilepsies/encephalopathies, primary rheumatologic conditions with central nervous system (CNS) manifestations, CNS vasculitis, and neurodegenerative/genetic conditions with immune-mediated pathophysiology and discuss epidemiology, pathophysiology, clinical presentation, treatment, and prognosis of each disorder. |
Databáze: | OpenAIRE |
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