Fertility and ovarian function are preserved in women treated with an intensified regimen of cyclophosphamide, adriamycin, vincristine and prednisone (Mega-CHOP) for non-Hodgkin lymphoma
| Autor: | Zeev Blumenfeld, Eldad J. Dann, Jacob M. Rowe, Nissim Haim, Menachem Ben Shahar, Ron Epelbaum, Irit Avivi |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Adult
medicine.medical_specialty Vincristine Cyclophosphamide medicine.medical_treatment CHOP Primary Ovarian Insufficiency Gastroenterology International Prognostic Index Prednisone Pregnancy Internal medicine Antineoplastic Combined Chemotherapy Protocols medicine Humans Chemotherapy business.industry Lymphoma Non-Hodgkin Rehabilitation Ovary Pregnancy Outcome Obstetrics and Gynecology Chemotherapy regimen Surgery Regimen Fertility Reproductive Medicine Doxorubicin Female business medicine.drug Follow-Up Studies |
| Zdroj: | Human reproduction (Oxford, England). 20(8) |
| ISSN: | 0268-1161 |
| Popis: | BACKGROUND: Intensive chemotherapy is widely used to improve the outcome of aggressive non-Hodgkin lymphoma (NHL). Since these regimens may cause premature ovarian failure (POF), the ovarian function was studied in 13 consecutive women aged ≤40 years, treated with four cycles of intensified CHOP (cyclophosphamide 2000-3000 mg/m 2 per cycle doxorubicin 50 mg/m 2 , vincristine 1.4 mg/m 2 (maximum 2mg) and prednisone 100 mg/day were given every 3 weeks). METHODS: Patients aged |
| Databáze: | OpenAIRE |
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