The impacts of cognitive-behavioral therapy on the treatment of phobic disorders measured by functional neuroimaging techniques: a systematic review

Autor: Fabiana Nery-Fernandes, Gerardo Maria de Araújo Filho, Andrea Parolin Jackowski, Amanda Cristina Galvão Oliveira de Almeida, Ângela Miranda-Scippa, Clarissa Trezsniak, Irismar Reis de Oliveira, Cesar Augusto Araujo Neto, Arthur A. Berberian
Přispěvatelé: Universidade Federal da Bahia School of Medicine Department of Neurosciences and Mental Health, Universidade Federal de São Paulo (UNIFESP), Faculdade de Medicina de São José do Rio Preto Department of Psychiatry and Medical Psychology, Universidade de São Paulo (USP), King's College London Institute of Psychiatry Department of Psychosis Studies, UFBA Medical School Department of Imaging Diagnosis
Rok vydání: 2013
Předmět:
Zdroj: Repositório Institucional da UNIFESP
Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
Repositório Institucional da UFBA
Universidade Federal da Bahia (UFBA)
instacron:UFBA
Brazilian Journal of Psychiatry v.35 n.3 2013
Brazilian Journal of Psychiatry (São Paulo. 1999. Online)
Associação Brasileira de Psiquiatria (ABP)
instacron:ABP
Brazilian Journal of Psychiatry, Vol 35, Iss 3, Pp 279-283 (2013)
Revista Brasileira de Psiquiatria, Volume: 35, Issue: 3, Pages: 279-283, Published: SEP 2013
ISSN: 1516-4446
DOI: 10.1590/1516-4446-2012-0922
Popis: Objective: Functional neuroimaging techniques represent fundamental tools in the context of translational research integrating neurobiology, psychopathology, neuropsychology, and therapeutics. In addition, cognitive-behavioral therapy (CBT) has proven its efficacy in the treatment of anxiety disorders and may be useful in phobias. The literature has shown that feelings and behaviors are mediated by specific brain circuits, and changes in patterns of interaction should be associated with cerebral alterations. Based on these concepts, a systematic review was conducted aiming to evaluate the impact of CBT on phobic disorders measured by functional neuroimaging techniques. Methods: A systematic review of the literature was conducted including studies published between January 1980 and April 2012. Studies written in English, Spanish or Portuguese evaluating changes in the pattern of functional neuroimaging before and after CBT in patients with phobic disorders were included. Results: The initial search strategy retrieved 45 studies. Six of these studies met all inclusion criteria. Significant deactivations in the amygdala, insula, thalamus and hippocampus, as well as activation of the medial orbitofrontal cortex, were observed after CBT in phobic patients when compared with controls. Conclusion: In spite of their technical limitations, neuroimaging techniques provide neurobiological support for the efficacy of CBT in the treatment of phobic disorders. Further studies are needed to confirm this conclusion. Universidade Federal da Bahia School of Medicine Department of Neurosciences and Mental Health Universidade Federal de São Paulo (UNIFESP) Department of Psychiatry Interdisciplinary Laboratory of Clinical Neurosciences Faculdade de Medicina de São José do Rio Preto Department of Psychiatry and Medical Psychology Universidade de São Paulo School of Medicine Department of Neuroscience and Behavior and National Science and Technology Institute for Translational Medicine King's College London Institute of Psychiatry Department of Psychosis Studies UFBA Medical School Department of Imaging Diagnosis UNIFESP, Department of Psychiatry Interdisciplinary Laboratory of Clinical Neurosciences SciELO
Databáze: OpenAIRE
Externí odkaz: