Infectious complications in neonatal transfusion: Narrative review and personal contribution
| Autor: | Giovanni Vento, Luciana Teofili, Nicoletta Orlando, Patrizia Papacci, Caterina Giovanna Valentini, Maria Bianchi |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Neonatal intensive care unit Congenital cytomegalovirus infection Cytomegalovirus 030204 cardiovascular system & hematology GVHD graft versus host disease PB peripheral blood Article Hepatitis 03 medical and health sciences 0302 clinical medicine Bacterial infections medicine Neonatal transfusion Humans Blood Transfusion Intensive care medicine Pathogen inactivation business.industry Donor selection Transfusion Medicine Infant Newborn Hematology CMV cytomegalovirus medicine.disease Cytomegalovirus infection HIV human immunodeficiency virus Leukoreduction HBV hepatitis B virus Settore MED/38 - PEDIATRIA GENERALE E SPECIALISTICA IUFT intrauterine fetal transfusion HCV hepatitis C virus Narrative review Female business 030215 immunology |
| Zdroj: | Transfusion and Apheresis Science |
| ISSN: | 1473-0502 |
| Popis: | Neonates and prematures are among the most transfused categories of patients. Adverse reactions due to transfusions, such as transfusion-transmitted infections, can affect the rest of their lives. In this systematic review, we revised the literature concerning transfusion-transmitted infection in neonates. We reported case-reports and case-series previously published and we integrated these data with our experience at local neonatal intensive care unit. Moreover, we illustrated strategies for mitigating transfusion-transmitted infections, including donor selection and testing, pathogen inactivation technologies and combined approaches, as for Cytomegalovirus infection, integrating leukoreduction and identification of seronegative donors. |
| Databáze: | OpenAIRE |
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