A Hot Topic: Cancer Immunotherapy and Natural Killer Cells
| Autor: | Markus W. Ollert, Tatiana Michel, Jacques Zimmer |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
QH301-705.5
Cell- and Tissue-Based Therapy Review Immunotherapy Adoptive Catalysis Inorganic Chemistry Antigens Neoplasm Neoplasms Animals Humans cancer Biology (General) Physical and Theoretical Chemistry QD1-999 Molecular Biology Spectroscopy Cancer natural killer cells Organic Chemistry Disease Management General Medicine Prognosis Computer Science Applications Killer Cells Natural Chemistry Treatment Outcome Natural killer cells Immunotherapy Disease Susceptibility immunotherapy Genetic Engineering |
| Zdroj: | International Journal of Molecular Sciences Michel, T, Ollert, M & Zimmer, J 2022, ' A Hot Topic : Cancer Immunotherapy and Natural Killer Cells ', International Journal of Molecular Sciences, vol. 23, no. 2, 797 . https://doi.org/10.3390/ijms23020797 International Journal of Molecular Sciences, Vol 23, Iss 797, p 797 (2022) |
| ISSN: | 1422-0067 |
| DOI: | 10.3390/ijms23020797 |
| Popis: | Despite significant progress in recent years, the therapeutic approach of the multiple different forms of human cancer often remains a challenge. Besides the well-established cancer surgery, radiotherapy and chemotherapy, immunotherapeutic strategies gain more and more attention, and some of them have already been successfully introduced into the clinic. Among these, immunotherapy based on natural killer (NK) cells is considered as one of the most promising options. In the present review, we will expose the different possibilities NK cells offer in this context, compare data about the theoretical background and mechanism(s) of action, report some results of clinical trials and identify several very recent trends. The pharmaceutical industry is quite interested in NK cell immunotherapy, which will benefit the speed of progress in the field. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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