Pretarsal blepharospasm: Clinical and electromyographic characteristics
| Autor: | A. Esteban, Alfredo Traba, Javier Ricardo Pérez-Sánchez, Francisco Grandas |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Botulinum Toxins Blepharospasm 050105 experimental psychology 03 medical and health sciences 0302 clinical medicine Physiology (medical) Ophthalmology medicine Excessive Blinking Humans 0501 psychology and cognitive sciences In patient Aged Orbicularis oculi muscle business.industry Electromyography 05 social sciences Eyelids Levator Palpebrae Superioris Middle Aged Botulinum toxin eye diseases Sensory Systems medicine.anatomical_structure Neurology Oculomotor Muscles Female sense organs Neurology (clinical) Eyelid medicine.symptom business Eye closure 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 131(7) |
| ISSN: | 1872-8952 |
| Popis: | Objective To describe the clinical and electromyographic characteristics of blepharospasm caused by selective involvement of the pars pretarsalis of the orbicularis oculi muscle. Methods Clinical assessment and simultaneous electromyographic recordings from levator palpebrae superioris and pars orbitaria and pretarsalis of orbicularis oculi muscles were performed in patients with blepharospasm and primary failure to botulinum toxin injections. Patients with selective abnormal electromyographic activity of the pars pretarsalis of the orbicularis oculi muscle were identified and treated with selective pretarsal injections of botulinum toxin. Results We found 24 patients with pretarsal blepharospasm confirmed by the electromyographic assessment. All of them were functionally blind. Three clinical-electromyographic patterns were identified: (a) Impairment of eyelid opening; (b) Increased blinking; (c) Spasms of eye closure combined with varying degrees of excessive blinking and impairment of eye-opening. Pretarsal injections of botulinum toxin induced a significant improvement in all patients and 50 % regained normal or near-normal vision. The clinical improvement was sustained after repeated pretarsal injections. Conclusions Pretarsal blepharospasm can be suspected on clinical grounds and it can be confirmed by electromyographic recordings. Significance Recognition of this type of blepharospasm is important because of its excellent response to botulinum toxin injections applied into the pretarsal part of the orbicularis oculi muscle. |
| Databáze: | OpenAIRE |
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