Glycemic load, glycemic index and carbohydrate intake in relation to risk of stomach cancer: A prospective study
Autor: | Susanna C. Larsson, Alicja Wolk, Leif Bergkvist |
---|---|
Rok vydání: | 2006 |
Předmět: |
Blood Glucose
Cancer Research medicine.medical_specialty Population Gastroenterology Stomach Neoplasms Internal medicine Glycemic load Dietary Carbohydrates Odds Ratio Humans Insulin Medicine Prospective Studies Insulin-Like Growth Factor I Refined grains education Stomach cancer Prospective cohort study Aged Glycemic Aged 80 and over Sweden education.field_of_study business.industry Incidence Middle Aged medicine.disease Glycemic index Endocrinology Oncology Glycemic Index Multivariate Analysis Female business Body mass index Follow-Up Studies |
Zdroj: | International Journal of Cancer. 118:3167-3169 |
ISSN: | 1097-0215 0020-7136 |
Popis: | The glycemic effects of diets high in refined grains and starchy foods might increase stomach cancer risk by affecting circulating glucose, insulin and insulin-like growth factor-I levels. No prospective data on the role of high glycemic load and glycemic index diets on stomach cancer risk have been reported. We therefore prospectively investigated dietary glycemic load, overall glycemic index and carbohydrate intake in relation to the incidence of stomach cancer among 61,433 women in the population-based Swedish Mammography Cohort. Diet was assessed at baseline (1987-1990) and again in 1997. During 903,586 person-years of follow-up, a total of 156 incident cases of stomach cancer were ascertained. We observed no material associations of dietary glycemic load, overall glycemic index and total carbohydrate intake with the risk of stomach cancer. The multivariate hazard ratios for the highest versus the lowest quintile were 0.76 (95% CI = 0.46-1.25) for glycemic load, 0.77 (95% CI = 0.46-1.30) for overall glycemic index and 0.85 (95% CI = 0.50-1.43) for carbohydrate intake. The associations did not vary according to body mass index. Lack of information on Helicobacter pylori infection status did not allow stratification by this potential effect modifier. Findings from this population-based prospective cohort of middle-aged and elderly women did not provide evidence of a positive association between glycemic load, glycemic index and carbohydrate intake with risk of stomach cancer. |
Databáze: | OpenAIRE |
Externí odkaz: |